Related Experiment Video
Updated: Jan 28, 2026

Author Spotlight: Tackling Challenges in Synthetic Cell Engineering
Published on: April 12, 2024
Comparison of physician networks constructed from thresholded ties versus shared clinical episodes
Jukka-Pekka Onnela1, A James O'Malley2, Nancy L Keating3,4
11Harvard T.H. Chan School of Public Health, Harvard University, 655 Huntington Avenue, Boston, MA USA.
Objective:
To compare standard methods for constructing physician networks from patient-physician encounter data with a new method based on clinical episodes of care.
Data Source:
We used data on 100% of traditional Medicare beneficiaries from 51 nationally representative geographical regions for the years 2005-2010.
Study Design:
We constructed networks of physicians based on their shared patients. In the fixed-threshold networks and adaptive-threshold networks, we included data on all patient-physician encounters to form the physician-physician ties, and then subsequently thresholded some proportion of the strongest ties. In contrast, in the episode-based approach, only those patient-physician encounters that occurred within shared clinical episodes treating specific conditions contributed towards physician-physician ties.
Data Collection/Extraction Methods:
We extracted clinical episodes in the Medicare data and investigated structural properties of the patient-sharing networks of physicians, temporal dynamics of their ties, and temporal stability of network communities across the two approaches.
Principal Findings:
The episode-based networks accentuated ties between primary care physicians (PCPs) and medical specialists, had ties that were more likely to reappear in the future, and appeared to have more fluid community structure.
Conclusions:
Constructing physician networks around shared episodes of care is a clinically sound alternative to previous approaches to network construction that does not require arbitrary decisions about thresholding. The resulting networks capture somewhat different aspects of patient-physician encounters.
More Related Videos
Related Concept Videos
Network Covalent Solids
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein Networks
The Sense of Self: Reflected Self-Appraisal and Social Comparison
Multiple Comparison Tests
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Evolutionary Relationships through Genome Comparisons

