[Management of functional bowel disorders].

Area of Science:

• Gastroenterology
• Functional Bowel Disorders Research

Background:

• Irritable bowel syndrome (IBS) and functional bloating are common gastrointestinal conditions.
• Pathogenic mechanisms are increasingly understood, leading to new treatment strategies.

Purpose of the Study:

• To review current and emerging therapeutic options for IBS and functional bloating.
• To highlight the role of non-pharmaceutical interventions and gut microbiota modulation.

Main Methods:

• Literature review of recent studies on IBS and functional bloating management.
• Analysis of established and novel treatment modalities.

Main Results:

• For IBS, therapeutic options include antispasmodics, alverine, laxatives, loperamide, low-dose antidepressants, and non-pharmaceutical approaches.
• Dietary advice, such as a low FODMAP diet, and gut microbiota treatments (probiotics, antibiotics) are increasingly recommended for IBS.
• Functional bloating management remains empirical, with proposed treatments including dietary modifications, simeticone, prokinetics, low-dose antidepressants, and microbiome modulation.

Conclusions:

• Enhanced understanding of IBS and functional bloating drives diverse therapeutic advancements.
• Low-dose antidepressants, dietary interventions, and gut microbiota modulation represent significant therapeutic options.