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Purification of a High Molecular Mass Protein in Streptococcus mutans
Published on: September 14, 2019
Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of
Lei Feng1, Qingsong Yan, Baojing Zhang
1College of Pharmacy, Academy of Integrative Medicine, National & Local Joint Engineering Research Center for Drug Development of Neurodegenerative Disease, Dalian Medical University, Dalian 116044, China. wach_edu@sina.com.
Abstract:
We report on a naphthalimide ratiometric fluorescent probe for the real-time sensing and imaging of pathogenic bacterial glucosyltransferases, which are associated with the development of dental caries. Using a high-throughput screening method, we identified that several natural polyphenols from green tea were GTFs inhibitors that could eventually lead to suitable oral treatments to prevent the development of dental caries.
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