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Native kidney BK nephropathy: A case report
Said Al Zein1, Hayley Price1, Guoli Chen1
1Penn State Health Milton S. Hershey Medical Center Hershey Pennsylvania.
Clinical Case Reports
|March 9, 2019
Summary
BK virus nephropathy (BKN) is rare in native kidneys, typically seen post-transplant. This case highlights BKN in native kidneys with high BK virus serum levels, offering new insights into viral nephropathy.
Area of Science:
- Nephrology
- Virology
- Transplant Medicine
Background:
- BK virus nephropathy (BKN) is a known complication, predominantly observed in hematopoietic stem cell transplant recipients.
- Its occurrence in native kidneys is infrequently documented, making such cases clinically significant.
Observation:
- This report details a unique case of biopsy-proven BK virus nephropathy in a patient's native kidneys.
- The patient presented with a substantial BK virus load in the serum, exceeding one million copies/mL.
Findings:
- The findings confirm the presence of BKN in native kidneys, challenging the conventional understanding of its typical presentation.
- High viral loads in serum correlate with the development of nephropathy in non-transplant native kidneys.
Implications:
- This case expands the spectrum of BKN presentation, emphasizing the need for vigilance in non-transplant native kidney settings.
- Further research may elucidate the mechanisms and risk factors for BKN in native kidneys, guiding diagnostic and therapeutic strategies.
Keywords:
BK virusbone marrow transplantimmunosuppressionkidney transplantnative BK virus nephropathyMore Related Videos
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