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Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain
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Advancing untargeted metabolomics using data-independent acquisition mass spectrometry technology

Ruohong Wang1,2, Yandong Yin1, Zheng-Jiang Zhu3

  • 1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China.

Analytical and Bioanalytical Chemistry
|March 9, 2019
PubMed
Summary

Data-independent acquisition (DIA) coupled with liquid chromatography-mass spectrometry (LC-MS) offers powerful untargeted metabolomics. This review covers DIA principles, data analysis, and its broad application potential in biological research.

Keywords:
Data-independent acquisitionMass spectrometryUntargeted metabolomics

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