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Updated: Jan 28, 2026

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Paradigms for Pharmacological Characterization of C. elegans Synaptic Transmission Mutants
Published on: August 18, 2008
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Liquid Active Zones for Controlling the Phases of Synaptic Transmission
Javier Emperador-Melero1, Pascal S Kaeser1
1Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Molecular Cell
|March 9, 2019
Abstract:
Wu et al. (2019) establish that the active zone proteins RIM and RIM-BP undergo liquid-liquid phase separation to tether Ca2+ channels. This important finding sets a new framework to study assembly and function of the presynaptic nerve terminal.
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