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Bilateral herpes simplex keratitis: lactation a trigger for recurrence!

Rinky Agarwal1, Prafulla Kumar Maharana1, Jeewan S Titiyal1

  • 1Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

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|March 11, 2019
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Summary
This summary is machine-generated.

A lactating woman with herpes simplex keratitis (HSK) was successfully treated with acyclovir and surgery. Continued breastfeeding was safe for the infant, demonstrating effective management of HSK in nursing mothers.

Keywords:
anterior chamberinfectious diseasesophthalmology

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Area of Science:

  • Ophthalmology
  • Virology
  • Neonatal care

Background:

  • Herpes simplex keratitis (HSK) presents unique challenges in lactating women due to potential viral transmission and treatment considerations.
  • Managing HSK in breastfeeding mothers requires a careful balance between maternal health and infant safety.

Observation:

  • A young lactating woman presented with simultaneous bilateral corneal lesions, clinically diagnosed as HSK.
  • Herpes simplex virus (HSV) PCR confirmed the diagnosis.
  • The patient received topical and systemic acyclovir, and underwent therapeutic penetrating keratoplasty in the right eye.

Findings:

  • The patient's HSK was successfully treated with a combination of acyclovir therapy and surgical intervention.
  • The infant remained clinically healthy at 3 months follow-up.
  • No adverse side effects of acyclovir were observed in either the mother or the baby.
  • The mother showed no recurrence of HSK in either eye at follow-up.

Implications:

  • This case highlights the safety and efficacy of managing HSK in lactating women with acyclovir and surgical treatment.
  • It underscores the importance of a multidisciplinary approach for optimizing outcomes in breastfeeding mothers with HSK.
  • Continued breastfeeding under strict hygienic conditions is feasible and safe during maternal HSK treatment.