Related Experiment Video
Updated: Jan 28, 2026
10:28
Direct Reprogramming of Human Fibroblasts into Myoblasts to Investigate Therapies for Neuromuscular Disorders
Published on: April 3, 2021
7.1K
Value of structured reporting in neuromuscular disorders.
Francesco Alessandrino1,2, Lara Cristiano3,4, Claudia Maria Cinnante5
1Neuroradiology Department, IRCCS C. Mondino Foundation, Pavia, Italy. falessandrino@bwh.harvard.edu.
La Radiologia Medica
|March 11, 2019
Summary
Structured reports (SRs) for inherited neuromuscular disorders (IND) MRI provide more clinically relevant information than non-structured reports (NSRs). SRs improve diagnostic accuracy and clinical decision-making, especially from less experienced radiologists.
Area of Science:
- Neurology
- Radiology
- Medical Imaging
Background:
- Inherited neuromuscular disorders (IND) require accurate MRI interpretation for diagnosis and management.
- Current non-structured reports (NSRs) may lack sufficient detail for optimal clinical decision-making.
- The impact of structured reporting (SR) and radiologist expertise on report quality is not fully understood.
Purpose of the Study:
- To compare the clinical relevance of structured reports (SRs) versus non-structured reports (NSRs) for MRI in IND patients.
- To evaluate how neuroradiologist expertise influences the completeness and utility of IND MRI reports.
Main Methods:
- Retrospective review of lower limb MRI reports (SRs and NSRs) from IND patients.
- Assessment of 9 key features and clinical utility by neurologists.
- Comparison of report quality based on radiologist experience (≥15 years vs. <15 years) and report type (SR vs. NSR).
Main Results:
- SRs contained significantly more key features (median 8) than NSRs (median 6).
- For less experienced radiologists, SRs improved pattern recognition, provided sufficient information for testing/biopsy, and reduced the need for image review compared to NSRs.
- Radiologist expertise did not significantly impact the utility of SRs, but affected NSR completeness.
Conclusions:
- Structured MRI reports for IND significantly enhance the inclusion of clinically relevant information.
- SRs are particularly beneficial for improving report quality from less experienced neuroradiologists.
- Radiologist expertise is a factor in the completeness of non-structured reports.
Related Concept Videos
02:18Intrinsically Disordered Proteins
19.4K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.4K
01:19The Neuromuscular Junction
18.7K
The nervous system consists of complex motor neuron circuits, including upper motor neurons originating from the cerebral cortex and lower motor neurons starting in the spinal cord, coordinating both voluntary and involuntary movements. Among these, somatic motor neurons activate skeletal muscles and are classified into alpha, beta, and gamma types. Alpha neurons are vital for voluntary movement coordination, while gamma neurons adjust muscle spindle sensitivity, and the function of beta...
18.7K
01:24Data Reporting and Recording
5.4K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K
01:25Types of Reports I: Hands-off Report
1.5K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
01:29Neuromuscular Junction And Blockade
5.0K
The site of chemical communication between a motor neuron and a muscle fiber is called the neuromuscular junction (NMJ). The end of the motor neuron at the NMJ divides into a cluster of synaptic end bulbs. The cytoplasm of these bulbs consists of synaptic vesicles enclosing acetylcholine molecules, the principal neurotransmitter released at the NMJ. The region opposite the synaptic bulb that ends in the muscle fiber is called the motor end plate, which has acetylcholine receptors. Within the...
5.0K
01:21Types of Reports II: Incident or Occurrence Report
1.2K
An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.2K