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Related Experiment Videos

Lactase deficiency and lactose malabsorption. A review.

P Enck, W E Whitehead

    Zeitschrift Fur Gastroenterologie
    |March 1, 1986
    PubMed
    Summary

    Lactase deficiency is genetically controlled but influenced by environmental factors. These factors, including diet and hormones, affect how individuals respond to lactose, impacting lactose malabsorption.

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    Area of Science:

    • Biochemistry
    • Genetics
    • Human Physiology

    Background:

    • Lactase deficiency and lactose malabsorption are common.
    • Previous research indicates a genetic basis for lactase activity decline.

    Purpose of the Study:

    • To review existing research on lactase deficiency.
    • To explore factors influencing lactose malabsorption.

    Main Methods:

    • Literature review of previous investigations.
    • Analysis of genetic and non-genetic factors.

    Main Results:

    • Lactase activity and its decline are genetically determined in humans and animals.
    • Phenotypic expression of lactose malabsorption is modulated by nongenetic factors.

    Conclusions:

    • Lactose malabsorption is not solely determined by genetics.
    • Adaptation, circadian rhythms, hormones, gut function, and nutrition significantly influence lactose digestion.

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