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Updated: Jan 28, 2026

Cryogenic Liquid Jets for High Repetition Rate Discovery Science
Published on: May 9, 2020
A versatile liquid-jet setup for the European XFEL
J Schulz1, J Bielecki1, R B Doak2
1European XFEL, Holzkoppel 4, Schenefeld 22869, Germany.
Abstract:
The SPB/SFX instrument of the European XFEL provides unique possibilities for high-throughput serial femtosecond crystallography. This publication presents the liquid-jet sample delivery setup of this instrument. The setup is compatible with state-of-the-art gas dynamic virtual nozzle systems as well as high-viscosity extruders and provides space and flexibility for other liquid injection devices and future upgrades. The liquid jets are confined in a differentially pumped catcher assembly and can be replaced within a couple of minutes through a load-lock. A two-microscope imaging system allows visual control of the jets from two perspectives.
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