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Published on: December 13, 2019
Analysis of echocardiographic parameters of cardiac function in patients with acute stroke
Anetta Lasek-Bal1, Amadeusz Żak2, Piotr Pysz3
1Department of Neurology, School of Health Sciences, Medical University of Silesia in Katowice, Poland. abal@sum.edu.pl.
Insights
Left ventricular systolic/diastolic dysfunction (LVSD) and low ejection fraction (EF) in stroke patients worsen neurological and functional outcomes. Lower EF and older age predict poor functional status one month post-stroke.
Area of Science:
- Cardiology
- Neurology
- Echocardiography
Background:
- Cardiologic diagnostics are crucial for identifying heart disease as a potential cause of stroke.
- Left ventricular systolic/diastolic dysfunction (LVSD) and low ejection fraction (EF) are common in stroke patients.
- Understanding their impact on neurological and functional status is vital for patient management.
Purpose of the Study:
- To evaluate the effect of low ejection fraction (EF) and left ventricular systolic/diastolic dysfunction (LVSD, LVDD) on neurological state on day 1 of stroke.
- To assess the impact of these cardiac conditions on post-stroke functional status at 30 days.
- To identify predictors of poor functional status after stroke.
Main Methods:
- A prospective study involving 162 stroke patients (mean age 74 years).
- Analysis included neurological state on day 1, transthoracic echocardiography results, and functional status at 30 days.
- Statistical analysis identified independent factors affecting stroke outcomes.
Main Results:
- Worse neurological state on day 1 was observed in patients with LVSD.
- Reduced EF was associated with significantly worse functional status at 30 days.
- Independent predictors for poor functional status included lower EF and older age.
Conclusions:
- Approximately 25% of acute stroke patients exhibit LVSD and/or LVDD.
- LVSD negatively impacts both acute neurological status and short-term functional recovery.
- Lower EF and advanced age are significant predictors of poor functional status one month post-stroke.
Introduction:
Cardiologic diagnostics in stroke patients is designed to identify heart disease as a potential cause of stroke. The aim of this study was to evaluate the effect of low ejection fraction (EF) and left ventricular systolic/diastolic dysfunction (LVSD, LVDD) on the neurological state on the 1st day of stroke, as well as post-stroke functional status at 30 days after stroke.
Patients And Methods:
For a prospective study, 162 stroke patients (mean age 74 years) were qualified. They were analysed according to neurological state on the 1st day of stroke, the results of transthoracic echocardiography, and functional status at 30 days after stroke.
Results:
The neurological state on the 1st day after stroke was significantly worse in patients with LVSD. In patients with reduced EF, functional status was significantly worse at 30 days after stroke. Patients with E/A 0.8-2 had a significantly worse functional status compared to patients with E/A < 0.8. Individuals with E/A 0.8-2 and segmental LVSD or EF < 50% had significantly worse functional status compared to patients without LVSD. An independent factor for moderate/severe status was identified: E/A > 0.8 (RR 3.28 [95% CI 1.15-9.37]); independent factors for poor functional status were lower EF (RR 4.68 [95% CI 1.22-18.00]) and age (RR 4.68 [95% CI 1.22-11.00]).
Conclusions:
One quarter of patients in the acute phase of stroke have LVSD and/or LVDD. LVSD adversely affects both neurological status in acute stroke as well as functional status in the short-term follow-up. Age at first-in-life stroke incidence and lower EF are predictors of poor functional status one month after a stroke.
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