Related Experiment Video
Updated: Jan 28, 2026

Laser Doppler Perfusion Imaging in the Mouse Hindlimb
Published on: April 18, 2021
Masimo Perfusion Index Versus Doppler for Tourniquet Effectiveness Monitoring
Background:
In addition to a plethysmograph, Masimo pulse oximeters display a Perfusion Index (PI) value. This study investigated the possible usefulness of PI for monitoring limb tourniquet arterial occlusion.
Methods:
Tactical Ratcheting Medical Tourniquets were applied to the thighs of 15 subjects. Tightening ended at one ratchet-tooth advance beyond Doppler- indicated occlusion. The times and pressures of Doppler and PI signal absences and returns were recorded.
Results:
Intermittent PI signal error occurred in 149 of 450 runs (PI, 33% versus Doppler, 0%; p < .0001). PI signal loss lagged Doppler-indicated occlusion by 19 ± 15 seconds (mean ± standard deviation, p < .0001). PI Signal Return lagged tourniquet release by 13 ± 7 seconds (Doppler Signal Return took 1 ± 1 seconds following tourniquet release; p < .0001). PI failed to detect early Doppler audible pulse return in 30 of 39 occurrences.
Conclusion:
The PI available on Masimo pulse oximeters is not appropriate for monitoring limb tourniquet effectiveness.
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