Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Primary Active Transport01:47

Primary Active Transport

197.9K
In contrast to passive transport, active transport involves a substance being moved through membranes in a direction against its concentration or electrochemical gradient. There are two types of active transport: primary active transport and secondary active transport. Primary active transport utilizes chemical energy from ATP to drive protein pumps that are embedded in the cell membrane. With energy from ATP, the pumps transport ions against their electrochemical gradients—a direction...
197.9K
Primary Active Transport01:29

Primary Active Transport

13.9K
In contrast to passive transport, active transport involves a substance being moved through membranes in a direction against its concentration or electrochemical gradient. There are two types of active transport: primary active transport and secondary active transport. Primary active transport utilizes chemical energy from ATP to drive protein pumps embedded in the cell membrane. With energy from ATP, the pumps transport ions against their electrochemical gradients—a direction they would...
13.9K
Primary and Secondary Growth in Roots and Shoots03:02

Primary and Secondary Growth in Roots and Shoots

60.4K
Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
60.4K
Primary Distribution01:28

Primary Distribution

540
Primary distribution systems deliver electrical power from substations to consumers through various voltage classes, with 15-kV class voltages being predominant among U.S. utilities. Older 2.5- and 5-kV classes are being replaced by 15-kV primaries, while higher 25- to 34.5-kV classes are used in high-density urban areas and rural regions with long feeders. Three-phase, four-wire multigrounded systems are widely employed for balanced power delivery, using the neutral wire as a grounding point.
540
Primary Production01:06

Primary Production

25.2K
The total amount of energy acquired by primary producers in an ecosystem is called gross primary production (GPP). However, of this energy, producers use some for metabolic processes, and some is lost as heat, decreasing the amount of energy available to the next trophic level. The remaining usable amount of energy is called the net primary productivity (NPP). In terrestrial ecosystems, NPP is driven by climate, while light penetration and nutrient availability drive NPP in aquatic ecosystems.
25.2K
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

15.6K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
15.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Conservatively managed non-functioning pituitary macroadenomas-cohort study from the UK Non-functioning Pituitary Adenoma Consortium.

European journal of endocrinology·2025
Same author

Outcomes after medical treatment for primary aldosteronism: an international consensus and analysis of treatment response in an international cohort.

The lancet. Diabetes & endocrinology·2025
Same author

Natural history of non-functioning pituitary microadenomas: results from the UK non-functioning pituitary adenoma consortium.

European journal of endocrinology·2023
Same author

Management of hypertensive emergencies and urgencies: narrative review.

Postgraduate medical journal·2023
Same author

Management of hypertensive emergencies and urgencies: narrative review.

Postgraduate medical journal·2023
Same author

Evaluating transition in Turner syndrome in the West of Scotland.

Journal of pediatric endocrinology & metabolism : JPEM·2021
Same journal

Resmetirom and semaglutide therapy for patients with MAFLD in the MENA region: expert panel recommendations.

Expert review of endocrinology & metabolism·2026
Same journal

The relationship between iron deficiency and thyroid function: findings from a population-based study in Jordan.

Expert review of endocrinology & metabolism·2026
Same journal

Beyond normalization: rethinking optimal prolactin levels in prolactinoma management.

Expert review of endocrinology & metabolism·2026
Same journal

Surgical considerations for adult Graves' disease: a narrative review of indications, perioperative challenges and postoperative outcomes.

Expert review of endocrinology & metabolism·2026
Same journal

Is metformin therapy limiting the benefits of exercise?

Expert review of endocrinology & metabolism·2026
Same journal

What is the role of amylin as an emerging therapeutic agent in obesity?

Expert review of endocrinology & metabolism·2026
See all related articles

Related Experiment Video

Updated: Jan 27, 2026

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.6K

Primary aldosteronism: an update.

E Marie Freel1, John Mc Connell2

  • 1a BHF Glasgow Cardiovascular Research Centre, 126 University Place, Glasgow, G12 8TA, UK. e.freel@clinmed.gla.ac.uk.

Expert Review of Endocrinology & Metabolism
|March 14, 2019
PubMed
Summary
This summary is machine-generated.

Primary aldosteronism (PA) is common and linked to hypertension and cardiovascular issues. Early diagnosis and treatment are crucial but challenging, necessitating optimized strategies.

Keywords:
adrenalaldosterone-to-renin ratiohypertensionprimary aldosteronism

More Related Videos

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)
09:38

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)

Published on: September 5, 2025

872
The Complete and Updated "Rotifer Polyculture Method" for Rearing First Feeding Zebrafish
08:52

The Complete and Updated "Rotifer Polyculture Method" for Rearing First Feeding Zebrafish

Published on: January 17, 2016

16.4K

Related Experiment Videos

Last Updated: Jan 27, 2026

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.6K
Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)
09:38

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)

Published on: September 5, 2025

872
The Complete and Updated "Rotifer Polyculture Method" for Rearing First Feeding Zebrafish
08:52

The Complete and Updated "Rotifer Polyculture Method" for Rearing First Feeding Zebrafish

Published on: January 17, 2016

16.4K

Area of Science:

  • Endocrinology
  • Cardiovascular Medicine
  • Nephrology

Background:

  • Primary aldosteronism (PA) affects 10% of hypertensive individuals, rising in resistant hypertension cases.
  • Aldosterone excess contributes to hypertension, cardiovascular morbidity, and adverse metabolic effects.
  • Accurate diagnosis and subtype determination for PA remain significant clinical challenges.

Purpose of the Study:

  • To review evidence on the increased prevalence of PA.
  • To explore the cardiovascular and metabolic consequences of aldosterone excess.
  • To discuss optimal diagnostic and therapeutic strategies for PA.

Main Methods:

  • Literature review of primary aldosteronism prevalence.
  • Analysis of studies on aldosterone's cardiovascular and metabolic effects.
  • Synthesis of current diagnostic and treatment guidelines for PA.

Main Results:

  • PA prevalence is higher than previously thought, especially in resistant hypertension.
  • Aldosterone excess significantly increases cardiovascular morbidity and metabolic disturbances.
  • Current diagnostic methods for PA can be complex and require refinement.

Conclusions:

  • Increased recognition of PA is vital for managing hypertension and reducing cardiovascular risk.
  • Addressing diagnostic challenges is key to timely PA identification and subtype classification.
  • Optimized therapeutic strategies are essential for improving patient outcomes in PA.