Association Of Degree Of St Segment Depression With Inhospital Mortality In Patients With Non-St Elevation Myocardial...

Area of Science:

• Cardiology
• Cardiovascular Medicine
• Clinical Research

Background:

• Ischemic heart disease causes one-third of global deaths, with Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) being a major cause of cardiac unit admissions.
• NSTE-ACS, a critical event in coronary artery disease, has a significant one-year mortality rate of 23.5%.
• Non-ST segment elevation myocardial infarction (NSTEMI) is a prevalent form of NSTE-ACS requiring urgent attention.

Purpose of the Study:

• To investigate the association between the degree of ST segment depression on electrocardiogram (ECG).
• To determine the predictive value of ST segment depression for in-hospital mortality in NSTEMI patients.

Main Methods:

• A descriptive case-series study was conducted at the Punjab Institute of Cardiology, Lahore.
• A total of 250 patients aged 30-75 years with NSTEMI were enrolled using non-probability purposive sampling.
• Data collected included demographic information, ECG findings, and in-hospital mortality outcomes.

Main Results:

• The study included 250 NSTEMI patients (mean age 54.64±9.69 years; 43.2% male, 56.8% female).
• The overall in-hospital mortality rate was 4.4% (11 out of 250 patients).
• A significant correlation was observed: mortality increased with a greater degree of ST segment depression on the admission ECG.

Conclusions:

• The degree of ST segment depression on admission ECG is a significant predictor of in-hospital mortality in NSTEMI patients.
• This finding aids in risk stratification and management of patients presenting with NSTEMI.
• Early identification of high-risk patients through ECG analysis can potentially improve outcomes.