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Updated: Jan 27, 2026

A Possible Zebrafish Model of Polycystic Kidney Disease: Knockdown of wnt5a Causes Cysts in Zebrafish Kidneys
Published on: December 2, 2014
[Polycystic kidney disease: diagnosis and progressive profile, prognostic elements]
1Service de néphrologie, CHU La Cavale blanche, université de Brest, Brest, France.
Abstract:
Polycystic kidney disease: diagnosis, progressive profile, prognostic elements. Autosomal dominant polycystic kidney disease can lead to end-stage renal disease but is also complicated by infectious, digestive, cardiovascular and hepatic problems. The diagnosis is easy in the presence of a family history, but its exclusion is sometimes difficult. Identification of clinical, morphologic and genetic progression factors has enabled to design prognostic scores currently used to assess the risk of progression of the disease and initiate specific therapies.
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