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Updated: Jan 27, 2026

Isolation of Valvular Endothelial Cells
Published on: December 29, 2010
Equine Acquired Valvular Disease
1Internal Medicine, Rossdales Equine Hospital and Diagnostic Centre, Cotton End Road, Exning, Newmarket, Suffolk CB8 7NN, UK.
Abstract:
Degenerative myxomatous disease is common and is associated with aging. Poor prognostic indicators for equine aortic regurgitation specifically include ventricular ectopy, increased pulse pressure, and hyperkinetic pulses. Valvular prolapse is a functional abnormality diagnosed echocardiographically, about which knowledge is limited. A better understanding of its role in valvular regurgitation is needed. Infective endocarditis presents with fever and other systemic signs accompanying valvular regurgitation. The prognosis is poor, warranting aggressive therapy. Other forms of valvular disease occur rarely, but often presenting with severe regurgitation. Management of horses with valvular disease is focused on assessment of severity and regular clinical, echocardiographic, and electrocardiographic monitoring.
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