Related Experiment Video
Updated: Jan 27, 2026

08:36
In Vivo Imaging to Measure Spontaneous Lung Metastasis of Orthotopically-injected Breast Tumor Cells
Published on: June 23, 2022
2.2K
How should complete lung collapse secondary to primary spontaneous pneumothorax be managed?
Muhammad Badar Ganaie1, Usman Maqsood2, Simon Lea3
1Royal Stoke University Hospital, Stoke-on-Trent, UK muhammad.ganaie@uhnm.nhs.uk.
Clinical Medicine (London, England)
|March 16, 2019
Summary
Intercostal drain (ICD) insertion is more immediately successful than needle aspiration (NA) for primary spontaneous pneumothorax with complete lung collapse. Long-term outcomes were similar between the two treatments.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Emergency Medicine
Background:
- Primary spontaneous pneumothorax (PSP) management varies based on symptoms and lung collapse severity.
- Current guidelines recommend needle aspiration (NA) followed by intercostal drain (ICD) if NA fails for PSP requiring intervention.
Purpose of the Study:
- To compare the efficacy of NA versus ICD as the initial treatment for PSP with complete lung collapse.
- To evaluate immediate and long-term success rates of different initial interventions.
Main Methods:
- Retrospective observational study of 877 pneumothorax episodes.
- Analysis of 69 PSP cases with complete lung collapse identified via Chest X-ray (CXR).
- Comparison of immediate lung re-inflation success between NA (n=35) and ICD (n=34) groups.
Main Results:
- ICD demonstrated significantly higher immediate success rates (62%) compared to NA (11%) (OR=12.5, p<0.0001).
- Adjusted analysis showed an increased odds ratio for ICD success (OR=26.4, p=0.0001).
- Long-term outcomes were comparable between the NA and ICD groups.
Conclusions:
- Intercostal drain (ICD) placement is a more effective first-line intervention for primary spontaneous pneumothorax with complete lung collapse.
- Consideration of ICD as the primary treatment for this specific PSP subgroup is warranted.
- Further consensus on the definition and management of complete lung collapse in PSP is needed.
Related Concept Videos
Primary and Secondary Growth in Roots and Shoots
60.4K
Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
60.4K
Pneumothorax-I
1.3K
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
1.3K
Primary and Secondary Reinforcers
920
In psychology, reinforcement is a key concept in behavior modification. B.F. Skinner demonstrated this with his experiments involving rats in what is known as a Skinner box. The rats learned to press a lever to receive food, a primary reinforcer that fulfilled their innate need for nourishment.
Effective reinforcers for humans vary depending on the individual and the context. Primary reinforcers, such as food, water, sleep, shelter, and pleasure, have inherent value and satisfy basic biological...
Effective reinforcers for humans vary depending on the individual and the context. Primary reinforcers, such as food, water, sleep, shelter, and pleasure, have inherent value and satisfy basic biological...
920
Pneumothorax-II
985
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
985
Spontaneity
29.7K
A spontaneous process is one that occurs naturally under certain conditions. A nonspontaneous process, on the other hand, will not take place unless it is “driven” by the continual input of energy from an external source. Processes have a natural tendency to occur in one direction under a given set of conditions. Water will naturally flow downhill (spontaneous process), but uphill flow (nonspontaneous process) requires outside intervention such as the use of a pump. Iron exposed to...
29.7K
Secondary Active Transport
137.7K
One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme “pump” embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...
137.7K

