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Updated: Jan 27, 2026

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
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Persistent Wheeze in Infants: A Guide for General Pediatricians.

Yolanda Yu, Charles R Esther, Clement L Ren

    Pediatric Annals
    |March 16, 2019
    PubMed
    Summary

    Persistent wheezing in infants presents a diagnostic challenge. Initial evaluation involves history, physical exam, and chest X-ray, with further tests and specialist consultation potentially needed.

    Area of Science:

    • Pediatrics
    • Pulmonology

    Background:

    • Persistent wheezing in infants is a frequent diagnostic dilemma for pediatricians.
    • A wide range of potential causes contributes to this diagnostic challenge.

    Purpose of the Study:

    • To outline an effective initial diagnostic approach for infants with persistent wheeze.
    • To guide general pediatricians in managing this common clinical scenario.

    Main Methods:

    • Review of current diagnostic strategies for infant persistent wheeze.
    • Emphasis on comprehensive history taking and physical examination.
    • Role of initial investigations like chest radiography.

    Main Results:

    • A structured approach is crucial for accurate diagnosis.

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  • Initial steps include thorough patient history, physical assessment, and chest imaging.
  • Further diagnostic testing and subspecialist referral may be necessary based on initial findings.

    • Conclusions:

    • The initial management of persistent wheeze in infants requires a systematic evaluation.
    • Key components include detailed history, physical exam, and chest radiography.
    • Subspecialty consultation should be considered when initial diagnostic measures are insufficient.