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Related Concept Videos

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Updated: Jan 27, 2026

Microfluidic Applications for Disposable Diagnostics
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Recent advances in thread-based microfluidics for diagnostic applications.

Xuan Weng1, Yuejun Kang2, Qian Guo1

  • 1School of Mechanical and Electrical Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan, 611731, China.

Biosensors & Bioelectronics
|March 16, 2019
PubMed
Summary
This summary is machine-generated.

Thread-based microfluidics offer advantages over paper systems for diagnostics and tissue engineering. This review highlights fabrication, detection techniques, and applications, paving the way for low-cost point-of-care devices.

Keywords:
ColorimetricCottonElectrochemicalPoint-of-careThread-based microfluidics

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Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Analytical Chemistry

Background:

  • Microfluidics research seeks improved substrate materials to overcome existing limitations.
  • Cellulose-based substrates like thread offer unique properties for diverse applications.
  • Thread-based microfluidics are emerging as a promising tool, particularly for diagnostic systems.

Purpose of the Study:

  • To provide a comprehensive review of thread-based microfluidic diagnostic devices.
  • To consolidate information on fabrication methods, detection techniques, and applications.
  • To identify future research directions for thread-based microfluidics.

Main Methods:

  • Literature review of recent advancements in thread-based microfluidics.
  • Analysis of fabrication techniques and their suitability for different applications.
  • Evaluation of detection methodologies and performance metrics for thread-based devices.

Main Results:

  • Thread-based microfluidics demonstrate significant potential in diagnostic systems, smart bandages, and tissue engineering.
  • Current fabrication methods and detection techniques are reviewed, showcasing diverse applications.
  • The field is still in its early stages, requiring further development for commercialization.

Conclusions:

  • Thread-based microfluidics represent a significant advancement with potential for low-cost, portable diagnostic tools.
  • Further research is needed to optimize fabrication, analytical strategies, and functionality.
  • The development of thread-based microfluidics could lead to accessible point-of-care diagnostic solutions.