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Updated: Jan 27, 2026

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Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
Published on: August 16, 2012
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Near-field Fourier ptychography: super-resolution phase retrieval via speckle illumination
Optics Express
|March 17, 2019
Summary
We introduce near-field Fourier ptychography, a new imaging technique that uses a low-resolution lens and a speckle pattern to achieve high spatial resolution in microscopy and macroscopy. This method bypasses the need for complex high-resolution optics.
Area of Science:
- Optics and Photonics
- Image Reconstruction
- Diffraction-Limited Imaging
Background:
- High spatial resolution is crucial for many imaging applications.
- Designing high-resolution lenses for large fields of view is challenging.
- Random diffusers can create wavelength-limited speckle patterns easily.
Purpose of the Study:
- To develop a novel imaging modality for high-resolution imaging.
- To address limitations of traditional high-resolution lens design.
- To enable high-resolution imaging in both microscopic and macroscopic settings.
Main Methods:
- Introduced near-field Fourier ptychography, utilizing a speckle pattern projected onto the object.
- Employed a low-resolution lens and translated the object or speckle pattern.
- Used ptychographic phase retrieval to reconstruct the object, speckle, and transfer function simultaneously.
Main Results:
- Achieved a numerical aperture (NA) of 0.85 from a 0.12 NA lens in microscopy.
- Obtained a ~7-fold resolution gain in macroscale photography.
- Demonstrated that speckle pattern feature size, not collection optics, dictates resolution.
Conclusions:
- Near-field Fourier ptychography offers a versatile solution for high-resolution imaging.
- The technique is applicable to light, X-ray, and electron imaging systems.
- Enables quantitative absorption and phase contrast imaging with enhanced resolution.
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