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A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy
Published on: May 16, 2015
The cost of care of the less-than-1000-gram infant
Insights
Aggressive treatment for extremely low birth weight (ELBW) infants is ethically justified, despite high costs and risks. Advances in perinatal medicine enable survival, with many survivors achieving normal or mild handicaps, offering significant societal and economic benefits.
Area of Science:
- Neonatal Intensive Care
- Perinatal Medicine
- Bioethics
Background:
- The ethical management of extremely low birth weight (ELBW) infants presents significant challenges in neonatal intensive care.
- Advances in perinatal medicine have improved survival rates for extremely premature infants.
Purpose of the Study:
- To evaluate the ethical considerations and effectiveness of aggressive medical intervention for ELBW infants.
- To determine if economic factors should influence treatment decisions for ELBW infants.
Main Methods:
- Review of current medical literature and survival statistics for ELBW infants.
- Analysis of the relationship between treatment costs, survival rates, and long-term quality of life.
Main Results:
- Aggressive treatment improves survival for ELBW infants, with many survivors experiencing normal or mild handicaps.
- Economic benefits and societal contributions from survivors are measurable, challenging cost-based arguments against intensive care.
- Neonatal intensive care is crucial for the survival of infants weighing less than 750 gm.
Conclusions:
- A policy of less aggressive treatment or benign neglect for ELBW infants is not supported by current medical evidence.
- Aggressive treatment is ethically and medically justifiable for ELBW infants, at least initially.
- The ethical dilemma of ELBW infant care transcends purely economic considerations.
Abstract:
One of the most difficult ethical issues in neonatal intensive care concerns the treatment of extremely low birth weight infants (ELBW). Because of their extreme prematurity, aggressive medical intervention is needed to sustain life. Advances in perinatal medicine have made it possible for these extremely immature infants to survive. More importantly, although the mortality and long-term morbidity are high, particularly for infants less than 700 gm, many of the survivors are expected to become productive members of society and produce measurable economic benefit. The limits set for aggressive management of the VLBW infant have gradually been lowered in virtue of the successful survival at each birth weight. It appears that, with each reduction in the birth weight at which maximal efforts should be used, enough babies have survived to encourage us to continue. As we drive to bring the limit of viability to lower gestations and lower birth weights, we are finding some biologic limitations to extrauterine survival that present technology and knowledge cannot overcome. Unquestionably, there is a need for more comprehensive statistics to allow us to define the lower limit of survival. Because of the poor survival rate among infants weighing less than 700 gm, and because of the high cost of their care and statistically poor quality of life among many of the surviving infants, it has been suggested that perhaps a less aggressive approach should be adopted for those extremely immature infants. However, some recent data indicate that aggressive treatment is effective in saving lives, even at the lower spectrum of birth weight, and many of the survivors are normal or have mild handicaps. The importance of economic considerations to solve the ethical dilemma posed by the intensive care of ELBW infants is being questioned. Concerns that reflect moral absolutes cannot be adequately answered in terms of mere dollars and cents. Although the cost of neonatal intensive care is high on a per diem or per case basis, it appears to be reasonable in relation to the health benefits it provides. For infants in the weight class less than 750 gm, probably none would have survived in the absence of neonatal intensive care. We believe that a policy of benign neglect for the ELBW infant is not justified in the present era of perinatal medicine. Given these considerations, we think that aggressive treatment is reasonable, at least initially at birth.(ABSTRACT TRUNCATED AT 400 WORDS)
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