Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

464
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
464
Overview of the Cardiovascular System01:14

Overview of the Cardiovascular System

11.7K
The cardiovascular system is a vital transportation system in the body. It comprises the heart and blood vessels and facilitates the exchange of gases, nutrients, and waste products.
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
11.7K
Regulation of the Cardiovascular System01:27

Regulation of the Cardiovascular System

3.9K
The regulation of the cardiovascular system allows the body to adapt to various demands and maintain homeostasis.
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
3.9K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

4.5K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
4.5K
Assessment of the Cardiovascular System II: Inspection01:29

Assessment of the Cardiovascular System II: Inspection

842
Inspection is the initial step in assessing the cardiovascular system. It involves a detailed visual examination that provides crucial information about a patient's circulatory and cardiac health. This systematic process, conducted from head to toe, helps identify signs of cardiovascular conditions by observing physical appearance, skin and mucous membranes, jugular and carotid pulsations, chest symmetry, and the condition of the extremities.
Head and Neck
842
Assessment of the Cardiovascular System IV: Auscultation01:25

Assessment of the Cardiovascular System IV: Auscultation

1.8K
Cardiac auscultation is a clinical skill used to assess heart function and detect abnormalities. It involves listening to heart sounds at specific anatomical locations through a stethoscope.
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biomarkers of Progressive Chronic Heart Failure: The Results of Blood Proteomic Analysis.

Kardiologiia·2026
Same author

Pulmonary Embolism Centers of Excellence: Current Protocols and Innovative Treatment Approaches.

Kardiologiia·2025
Same author

Long-Term Thrombotic Events in Patients with Myocardial Infarction: Proteomic Analysis of Platelets and Plasma Combined with Hemostasis Assessment.

Kardiologiia·2025
Same author

[Study of the role of biomarkers in determining the course of non-alcoholic fatty liver disease in children with obesity].

Voprosy pitaniia·2025
Same author

Peculiarities of Hemostasis and Proteomics in Patients With Acute Myocardial Infarction and Healthy Volunteers After SARS-CоV-2 Infection.

Kardiologiia·2024
Same author

[Comparative aspect of normative (reference) values of indicators of length and weight of children living in the region of the Far North (part 1 - body length indicators)].

Problemy sotsial'noi gigieny, zdravookhraneniia i istorii meditsiny·2023

Related Experiment Video

Updated: Jan 27, 2026

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
05:53

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Published on: July 6, 2013

15.5K

Cytomegalovirus Infection in Cardiovascular Diseases.

A M Lebedeva1, A V Shpektor2, E Yu Vasilieva2

  • 1Department of Cardiology and Laboratory of Atherothrombosis, A. I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation, Moscow, 127473, Russia. asya.lebedev@mail.ru.

Biochemistry. Biokhimiia
|March 18, 2019
PubMed
Summary
This summary is machine-generated.

Cytomegalovirus (CMV) infection activation is linked to acute coronary syndrome and atherosclerotic plaque expansion. CMV spreads via extracellular vesicles, triggering immune responses and endothelial dysfunction in cardiovascular disease.

More Related Videos

In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

2.2K
Digital PCR for Quantifying Circulating MicroRNAs in Acute Myocardial Infarction and Cardiovascular Disease
04:41

Digital PCR for Quantifying Circulating MicroRNAs in Acute Myocardial Infarction and Cardiovascular Disease

Published on: July 3, 2018

8.7K

Related Experiment Videos

Last Updated: Jan 27, 2026

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
05:53

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Published on: July 6, 2013

15.5K
In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

2.2K
Digital PCR for Quantifying Circulating MicroRNAs in Acute Myocardial Infarction and Cardiovascular Disease
04:41

Digital PCR for Quantifying Circulating MicroRNAs in Acute Myocardial Infarction and Cardiovascular Disease

Published on: July 3, 2018

8.7K

Area of Science:

  • Cardiovascular Medicine
  • Infectious Diseases
  • Immunology

Background:

  • Atherosclerosis is a primary cause of cardiovascular disease mortality.
  • Activated immune cells play a role in atherosclerosis, but mechanisms are unclear.
  • Chronic inflammation in atherosclerosis suggests infectious agent involvement.

Purpose of the Study:

  • To review the role of cytomegalovirus (CMV) infection in atherosclerosis progression.
  • To discuss mechanisms linking CMV infection to plaque expansion and cardiovascular events.
  • To explore CMV's impact on immune activation and endothelial function.

Main Methods:

  • Review of existing research on CMV infection and cardiovascular disease.
  • Analysis of data on CMV's association with acute coronary syndrome and myocardial infarction.
  • Investigation of virus transfer via extracellular vesicles in the vascular wall.

Main Results:

  • CMV infection activation correlates with acute coronary syndrome.
  • CMV spreads to immune and endothelial cells, potentially via extracellular vesicles.
  • Productive CMV infection is linked to increased endothelial dysfunction in myocardial infarction patients.

Conclusions:

  • CMV infection contributes to atherosclerotic plaque expansion in ischemic heart disease.
  • CMV-induced immune activation and endothelial dysfunction are key mechanisms.
  • CMV plays a significant role in the pathogenesis of atherosclerosis and related cardiovascular diseases.