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Flexible and Superwettable Bands as a Platform toward Sweat Sampling and Sensing
Xuecheng He1, Tailin Xu1, Zhen Gu1
1Research Center for Bioengineering and Sensing Technology, Department of Chemistry and Biological Engineering , University of Science and Technology Beijing , Beijing 100083 , P. R. China.
Analytical Chemistry
|March 19, 2019
Summary
This study presents a novel wearable biosensor band for on-body sweat analysis. The superwettable band precisely collects sweat for cellphone-based biodetection of key health markers.
Area of Science:
- Biomedical Engineering
- Materials Science
- Analytical Chemistry
Background:
- Wearable biosensors are advancing healthcare by integrating diagnostics into portable devices.
- Current methods for sweat analysis face challenges in precise sample collection and on-site analysis.
Purpose of the Study:
- To develop a flexible, skin-mounted biosensor band for in situ sweat sampling and analysis.
- To enable noninvasive, cellphone-based detection of multiple biomarkers in sweat.
Main Methods:
- Fabrication of a superhydrophobic-superhydrophilic microarray on a flexible band.
- Utilizing nanodendritic colorimetric biosensors for sweat analysis.
- Demonstrating on-body sweat collection and confinement using superwettable surfaces.
Main Results:
- The superwettable band precisely collected sweat microdroplets with minimal spreading.
- Successful cellphone-based detection of pH, chloride, glucose, and calcium in sweat.
- Demonstrated improved interface controllability for epidemical sweat sampling.
Conclusions:
- The developed wearable biosensor band offers a promising platform for facile and noninvasive biofluid analysis.
- Superwettable surfaces enhance sweat sampling accuracy and site control for wearable diagnostics.
- This technology holds potential for widespread application in personalized healthcare and remote monitoring.
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