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Paronychia Associated with Ledipasvir/Sofosbuvir for Hepatitis C Treatment
Blake Sampson1,2, Bethany K H Lewis1,2
1Dr. Sompson is with the Oregon MedicoI Group in Eugene/Springfield, Oregon (with the Deportment of Dermatology at University of Utah in Salt Lake City, Utah (at the time of this work).
Abstract:
We present a case of medication-associated paronychia involving multiple toenails in a patient undergoing hepatitis C (HCV) therapy with ledipasvir/sofosbuvir. The patient was treated conservatively with topical mupirocin, clobetasol ointment, and acetic acid soaks, resulting in symptom improvement and control. This topical regimen was maintainined throughout the remaining weeks of the patient's antiviral course, with complete symptom resolution occurring only after completion of his ledipasvir/sofosbuvir treatment.
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