Related Experiment Video
Updated: Jan 27, 2026

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
Published on: August 21, 2017
Neuromyelitis optica after splenectomy: A secondary autoimmune phenomenon
James M Hillis1, Farrah J Mateen1
1Massachusetts General Hospital, Department of Neurology, 165 Cambridge St., Boston, MA 02114, USA.
Abstract:
We describe the case of a 53-year-old woman who undergoes total splenectomy and later presents with aquaporin-4 antibody positive neuromyelitis optica (NMO). The occurrence of NMO after acquired immunosuppression raises the possibility of NMO as a form of secondary autoimmunity.
Related Concept Videos
Tip-of-the-Tongue Phenomenon
Secondary Active Transport
Secondary Active Transport
Secondary Healthcare System
Primary and Secondary Growth in Roots and Shoots
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...

