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Prescribed daily dose of phenoxymethylpenicillin in general practice
Scandinavian Journal of Primary Health Care
|May 1, 1986
Abstract:
Prescribed daily dose (PDD) of phenoxymethylpenicillin was estimated in a multipractice study in 1979 and in 1983. PDD increased from 2.08 mio IU in 1979 to 2.32 mio IU in 1983. PDD was independent of number of daily doses, and factors related to practice. Only slight variations with diagnosis and doctor's age was found.
Insights
The prescribed daily dose (PDD) for phenoxymethylpenicillin increased between 1979 and 1983. This antibiotic dosage trend was largely unaffected by practice-related factors or the number of daily doses administered.
Area of Science:
- Pharmacology
- Clinical Pharmacy
- Drug Dosing
Background:
- Phenoxymethylpenicillin is a widely prescribed antibiotic.
- Understanding prescribed daily doses (PDD) is crucial for antimicrobial stewardship.
- Variations in PDD can impact treatment efficacy and resistance patterns.
Purpose of the Study:
- To estimate the prescribed daily dose (PDD) of phenoxymethylpenicillin.
- To analyze trends in PDD over time.
- To identify factors influencing PDD variations.
Main Methods:
- A multipractice study design was employed.
- Data collection occurred in 1979 and 1983.
- Statistical analysis was performed to assess PDD and influencing factors.
Main Results:
- The PDD of phenoxymethylpenicillin rose from 2.08 million international units (IU) in 1979 to 2.32 million IU in 1983.
- PDD showed independence from the number of daily doses and practice-related factors.
- Minor variations in PDD were observed concerning diagnosis and physician age.
Conclusions:
- A notable increase in the prescribed daily dose of phenoxymethylpenicillin occurred between 1979 and 1983.
- Prescribing habits for this antibiotic appear relatively consistent across different practice settings and dosing frequencies.
- Further research may explore the clinical implications of these PDD trends.