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Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
5.4K
Precision medicine in Thailand
Vorasuk Shotelersuk1,2, Sissades Tongsima3, Manop Pithukpakorn4,5
1Center of Excellence for Medical Genomics, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Summary
Advances in next-generation sequencing (NGS) are driving precision medicine in Thailand. This summary reviews current infrastructure and adoption in rare diseases, oncology, pharmacogenomics, and NCDs, highlighting future needs.
Area of Science:
- Genomics and Bioinformatics
- Translational Medicine
- Public Health
Background:
- High-throughput next-generation sequencing (NGS) and bioinformatics are transforming healthcare towards precision medicine.
- Precision medicine integrates individual variability into clinical practice.
- Thailand is assessing its readiness for precision medicine implementation.
Purpose of the Study:
- To summarize the current status of precision medicine infrastructure and adoption in Thailand.
- To review progress in four key areas: rare diseases, oncology, pharmacogenomics, and noncommunicable diseases.
- To provide perspectives on future challenges, including workforce development and ethical, legal, and social issues.
Main Methods:
- Review of existing infrastructure for precision medicine in Thailand.
- Assessment of adoption levels across specified healthcare spheres.
- Analysis of future requirements and potential barriers.
Main Results:
- Current infrastructure and adoption status in Thailand for precision medicine are detailed.
- Progress and challenges are outlined for rare diseases, oncology, pharmacogenomics, and noncommunicable diseases.
- Key considerations for future implementation, including manpower and ethical, legal, and social implications, are discussed.
Conclusions:
- The decreasing cost of NGS and improving data interpretation capabilities support precision medicine.
- Increased availability of actionable treatments is a key driver for adoption.
- The implementation of precision medicine in Thailand's public health system is considered inevitable.
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