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Updated: Jan 27, 2026

Reconstitution of a Kv Channel into Lipid Membranes for Structural and Functional Studies
Published on: July 13, 2013
Emerging structural biology of TRPM subfamily channels
Yixiang Chen1, Xu Zhang2, Tingting Yang3
1School of Basic Medical Sciences, Nanchang University, Nanchang, 330031, Jiangxi, China.
Abstract:
TRPM family (Transient receptor potential channels, M for melastatin) is a group of intrinsic plasma membrane ion channels which are widely expressed throughout human body. It has been identified as a potent entry point of working desperate diseases out in a new way with newfangled ideas and safer technological means. In our review, we discussed the common and unique properties of TRPM family with the elaborate narrate in their overall structures, different states and the underlying activation mechanism. Thus, this review can help to consummate the limited work of TRPM family and provide novel therapeutic targets of certain diseases.
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