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Updated: Jan 27, 2026
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Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition
Published on: August 18, 2023
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Optic Nerve Sheath Diameter for Preterm Infants: A Pilot Study
Sarah Ardell1, Sibasis Daspal2, Tanya Holt3
1College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Neonatology
|March 20, 2019
Summary
Optic nerve sheath diameter (ONSD) ultrasonography offers a noninvasive method for assessing intracranial pressure (ICP) in preterm infants. This pilot study found ONSD measurements strongly correlate with corrected gestational age in this population.
Area of Science:
- Neonatal Medicine
- Pediatric Neurology
- Medical Imaging
Background:
- Early detection of raised intracranial pressure (ICP) is crucial for neurodevelopmental outcomes in preterm infants.
- Invasive ICP monitoring is not recommended for neonates.
- Optic nerve sheath diameter (ONSD) ultrasonography presents a noninvasive alternative for ICP evaluation.
Purpose of the Study:
- To establish normative ranges of ONSD in preterm infants.
- To investigate the correlation between ONSD and corrected gestational age.
- To assess the feasibility of ONSD as a noninvasive ICP indicator in neonates.
Main Methods:
- Prospective cohort pilot study of preterm infants in the NICU.
- Ultrasound imaging of ONSD using a 20-5 MHz linear array transducer.
- Measurement of ONSD 3 mm behind the globe; interrater reliability assessed.
Main Results:
- 114 scans were performed on 12 preterm infants (median corrected gestational age 33 weeks).
- Corrected gestational age was the strongest predictor for ONSD.
- Substantial interrater reliability (Qc = 0.97) was demonstrated.
Conclusions:
- ONSD in preterm infants shows a strong correlation with corrected gestational age.
- Preliminary ONSD ranges were established based on gestational age.
- Further validation with other imaging modalities is needed before clinical application for abnormal ranges.
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