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Updated: Jan 27, 2026

Preparation of Quality Inositol Pyrophosphates
Published on: September 3, 2011
Updated Treatment for Calcium Pyrophosphate Deposition Disease: An Insight
Shumaila M Iqbal1, Sana Qadir2, Hafiz M Aslam3
1Internal Medicine, University at Buffalo / Sisters of Charity Hospital, Buffalo, USA.
Abstract:
Calcium pyrophosphate disease (CPPD) is caused by the deposition of calcium pyrophosphate (CPP) crystals in the joint tissues, particularly fibrocartilage and hyaline cartilage. CPP crystals trigger inflammation, causing local articular tissue damage. Our review article below covers different aspects of CPPD. It discusses how CPPD can manifest as different kinds of arthritis, which may be symptomatic or asymptomatic. The metabolic and endocrine disease associations and routine investigations used in the diagnostic workup are briefly reviewed. Conventional and newer therapies for the treatment of CPPD are outlined. Overall, this extensive review would provide an updated insight to clinicians for evidence-based treatment of CPPD.
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