Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models01:06

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

246
Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
246
Drug Distribution: Volume of Distribution01:25

Drug Distribution: Volume of Distribution

7.4K
The volume of distribution refers to the theoretical volume necessary to contain the entire amount of an administered drug at the same concentration observed in the blood plasma. The body's intracellular fluid compartment, which makes up two-thirds of the total body water, is contrasted with the extracellular fluid compartment—comprising plasma and interstitial fluid—that accounts for one-third. The volume of distribution can vary depending on the characteristics of the drug.
7.4K
F Distribution01:19

F Distribution

10.7K
The F distribution was named after Sir Ronald Fisher, an English statistician. The F statistic is a ratio (a fraction) with two sets of degrees of freedom; one for the numerator and one for the denominator. The F distribution is derived from the Student's t distribution. The values of the F distribution are squares of the corresponding values of the t distribution. One-Way ANOVA expands the t test for comparing more than two groups. The scope of that derivation is beyond the level of this...
10.7K
Optimal Foraging00:48

Optimal Foraging

13.8K
How animals obtain and eat their food is called foraging behavior. Foraging can include searching for plants and hunting for prey and depends on the species and environment.
13.8K
Optimization Problems01:26

Optimization Problems

62
Optimization problems often involve identifying maximum or minimum values under specific constraints. A well-known example is determining the longest horizontal pipe that can be moved around a right-angled corner, where a 3-meter-wide hallway meets a 2-meter-wide hallway. This scenario, common in architectural design and industrial transport, can be understood conceptually through geometric and trigonometric reasoning.To visualize the problem, consider the pipe as a straight line that touches...
62
Volume of Distribution01:20

Volume of Distribution

1.2K
The apparent volume of distribution (Vd) is a crucial pharmacokinetic parameter representing the hypothetical body fluid volume into which a drug disperses. It is calculated based on the total amount of drug in the body (estimated from the administered dose and bioavailability) divided by the plasma drug concentration. The total amount of drug in the body does not directly refer to the dose given but is derived by accounting for absorption, distribution, metabolism, and excretion processes.
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thermodynamics and Kinetics Study on the Reactive Crystallization Process of Cerium Oxalate.

ACS omega·2026
Same author

Preclinical efficacy of engineered CircRNA-GDF15@LNP for sustained weight loss and metabolic regulation in diet-induced obese mice.

Journal of controlled release : official journal of the Controlled Release Society·2026
Same author

The SIRT1-p53 axis drives a ferro-aging-like program and aggravates trophoblast dysfunction in preeclampsia.

Frontiers in aging·2026
Same author

Specific inhibition of NLRP3 inflammasome by a Smurf1 inhibitor <i>in vitro</i> and <i>in vivo</i>.

Open medicine (Warsaw, Poland)·2026
Same author

Preparation of Fe<sub>2</sub>O<sub>3</sub>/GCN/ICG/DHA Nanocomplexes and Their Multifunctional Combined Antitumor Properties.

International journal of nanomedicine·2026
Same author

Multi-omics integration reveals tumor and microenvironmental heterogeneity in malignant pleural mesothelioma.

Discover oncology·2026
Same journal

A New Human-Likeness and Comfort Index for Robot Movements Along Prescribed Paths.

IEEE transactions on cybernetics·2026
Same journal

Robust Semiglobal and Global Stabilization for Nonlinear Normal Form Systems by Time-Varying Feedback.

IEEE transactions on cybernetics·2026
Same journal

Adaptive Global Asymptotic Output Stabilization of Uncertain Nonlinear Systems Under Dynamic State/Input Quantization.

IEEE transactions on cybernetics·2026
Same journal

Accelerated Distributed Gradient Tracking for Constrained Aggregative Optimization Over Time-Varying Digraphs.

IEEE transactions on cybernetics·2026
Same journal

Small-Gain-Based Plug-and-Play Distributed Control Framework for DC Microgrids With Decentralized Reconfiguration.

IEEE transactions on cybernetics·2026
Same journal

Prescribed-Time Impulsive Control of High-Order Integrator Systems.

IEEE transactions on cybernetics·2026
See all related articles

Related Experiment Video

Updated: Jan 27, 2026

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
08:45

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

15.2K

A Novel Multiagent Neurodynamic Approach to Constrained Distributed Convex Optimization.

Litao Ma, Wei Bian

    IEEE Transactions on Cybernetics
    |March 21, 2019
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a new multiagent neurodynamic method for distributed convex optimization problems with constraints. The approach ensures consensus and convergence to optimal solutions for complex, real-world applications like power systems.

    More Related Videos

    Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
    03:43

    Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

    Published on: July 11, 2025

    702
    An Inverse Analysis Approach to the Characterization of Chemical Transport in Paints
    08:42

    An Inverse Analysis Approach to the Characterization of Chemical Transport in Paints

    Published on: August 29, 2014

    8.7K

    Related Experiment Videos

    Last Updated: Jan 27, 2026

    Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
    08:45

    Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

    Published on: October 24, 2012

    15.2K
    Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
    03:43

    Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

    Published on: July 11, 2025

    702
    An Inverse Analysis Approach to the Characterization of Chemical Transport in Paints
    08:42

    An Inverse Analysis Approach to the Characterization of Chemical Transport in Paints

    Published on: August 29, 2014

    8.7K

    Area of Science:

    • Control Systems Engineering
    • Optimization Theory
    • Computational Neuroscience

    Background:

    • Distributed convex optimization problems are crucial in multiagent systems.
    • Existing methods often struggle with general constraints and communication bandwidth.
    • Nonsmooth convex functions and local constraints present significant challenges.

    Purpose of the Study:

    • To propose a novel continuous-time multiagent neurodynamic approach for distributed convex optimization with general constraints.
    • To ensure asymptotic consensus and convergence to optimal solutions for all agents.
    • To develop a method with low structure complexity suitable for constrained problems.

    Main Methods:

    • A continuous-time multiagent neurodynamic system is formulated.
    • Each agent individually solves its objective function.
    • Analysis guarantees the existence, boundedness, and convergence of state solutions.

    Main Results:

    • The proposed neurodynamic system guarantees the existence and boundedness of global state solutions.
    • State solutions asymptotically reach the feasible region of the equivalent optimization problem.
    • Agent outputs converge to the optimal solution set of the primal distributed problem.

    Conclusions:

    • The novel neurodynamic approach is effective for general constrained distributed optimization problems.
    • The method offers low structure complexity, reducing communication bandwidth requirements.
    • Demonstrated efficiency in numerical examples and power system optimal load-sharing problems.