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Prevalence and risk factors for perioperative complications of CKD patients undergoing elective hip surgery
Yongqing You1, Yijian Zhang2, Lei Qiang3,4
1Department of Nephrology, Affiliated Hospital of Nanjing Medical University, North District of Suzhou Municipal Hospital, Suzhou, China. youyongiqngabc@163.com.
Insights
Patients with chronic kidney disease (CKD) face higher risks of blood transfusions and ICU transfers after hip surgery. Addressing preoperative anemia is crucial for reducing transfusion rates in CKD patients undergoing orthopedic procedures.
Area of Science:
- Nephrology
- Orthopedic Surgery
- Critical Care Medicine
Background:
- Chronic kidney disease (CKD) is a significant risk factor for increased morbidity and mortality following orthopedic surgery.
- Understanding the specific perioperative challenges faced by hip surgery patients with CKD is essential for improving outcomes.
Purpose of the Study:
- To investigate the impact of chronic kidney disease (CKD) on perioperative complications in patients undergoing hip surgery.
- To identify risk factors associated with adverse outcomes in this patient population.
Main Methods:
- A cohort study involving 230 hip surgery patients (30 with CKD, 200 without) from 2013-2016.
- Collection and analysis of preoperative, intraoperative, and postoperative data comparing CKD and non-CKD groups.
- Logistic regression analysis to determine independent risk factors for postoperative complications.
Main Results:
- CKD patients exhibited higher rates of preoperative comorbidities including hypertension, diabetes, coronary heart disease, and anemia.
- CKD patients were significantly more likely to receive blood transfusions (50% vs 28.5%) and transfer to the ICU (73.3% vs 19.3%).
- Independent risk factors for blood transfusion included diabetes, alcohol use, and anemia; factors for ICU transfer included age, CKD, and osteoporosis.
Conclusions:
- Hip surgery patients with CKD present with more cardiac comorbidities preoperatively.
- CKD is associated with an increased likelihood of requiring blood transfusions and ICU admission post-hip surgery.
- Optimizing preoperative anemia in CKD patients may reduce the incidence of blood transfusions and associated complications.
Purpose:
Chronic kidney disease (CKD) is known to increase morbidity and mortality after orthopedic surgery. The purpose of this study is to investigate how CKD affects perioperative complications in hip surgery patients.
Material And Methods:
From 2013 to 2016, a total of 230 patients (30 patients with CKD and 200 without CKD) undergoing hip surgery were enrolled in this study. Preoperative, intraoperative, and postoperative data was collected and analyzed between CKD and non-CKD patients. Logistic regression was used to evaluate the independent risk factor for postoperative complications.
Results:
There were significant differences in the number of people with hypertension (90.0% vs 27.3%, P < 0.001), diabetes (33.3% vs 8.7%, P = 0.01), coronary heart disease (20.0% vs 2.0%, P = 0.001), smoking habits (56.7% vs 22.7%, P = 0.016), anemia (90.0% vs 19.3%, P < 0.001), and low hemoglobin levels (94.1 ± 19.7 vs 121.3 ± 18.8, P < 0.001) between CKD and non-CKD patients before surgery. Receiving a blood transfusion was significantly more common in CKD patients (50% vs 28.5%, P = 0.018). Postoperatively, significant differences were detected in the average number of patients who transferred to the ICU (73.3% vs 19.3%, P < 0.001). Furthermore, differences were found in the quantity of hemoglobin (92.5 ± 16.8 vs 107.5 ± 18.3, P < 0.001) and albumin (32.4 ± 4.1 vs 34.9 ± 5.5, P = 0.02) measured between CKD and non-CKD patients. Logistic regression analysis indicated that diabetes, alcohol, and anemia were all independent risk factors for obtaining a blood transfusion, while age, CKD, and osteoporosis were all independent risk factors for ICU transfers.
Conclusion:
Compared with non-CKD patients, CKD patients were accompanied with more cardiac diseases preoperatively. In addition, CKD patients were more likely to receive a blood transfusion and transfer to the ICU after hip surgery. Preoperative anemia should be restored sufficiently to decrease the incidence of blood transfusions.
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