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Updated: Jan 27, 2026

08:19
Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
Published on: January 15, 2016
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2,7-Diazabicyclo[2.2.1]heptanes: novel asymmetric access and controlled bridge-opening
Gary R Peczkowski1, Philip G E Craven, Darren Stead
1School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. N.Simpkins@bham.ac.uk.
Abstract:
Organocatalysed asymmetric Michael additions of substituted triketopiperazines to enones afford products in high yield and enantiomeric ratio (er). Further modification delivers products possessing natural product (NP) scaffolds including diazabicyclo[2.2.1]heptane, prolinamide and harmicine.
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