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Published on: September 25, 2017
Electrocardiographic criteria for left ventricular hypertrophy in aortic valve stenosis: Correlation with
Karolina Bula1, Anna Ćmiel2, Monika Sejud2
1First Department of Cardiology, School of Medicine in Katowice, Upper Silesian Medical Centre, Medical University of Silesia, Katowice, Poland.
Insights
Electrocardiogram (ECG) criteria for left ventricular hypertrophy (LVH) are not sensitive in detecting LVH in patients with aortic stenosis (AS). While present in 59% of patients, ECG findings weakly correlate with echocardiographic measures of AS severity.
Area of Science:
- Cardiology
- Medical Diagnostics
Background:
- Aortic stenosis (AS) causes chronic pressure overload, leading to left ventricular hypertrophy (LVH).
- Assessing LVH in AS patients is crucial for understanding disease progression and management.
Purpose of the Study:
- To determine the prevalence of electrocardiographic (ECG) criteria for LVH in patients with significant AS.
- To evaluate the correlation between ECG-detected LVH and echocardiographic parameters in these patients.
Main Methods:
- Retrospective analysis of clinical data from 95 patients with moderate to severe AS.
- Comparison of eight ECG criteria for LVH against transthoracic echocardiography (TTE) results.
Main Results:
- At least one ECG criterion for LVH was identified in 59% of patients.
- ECG-positive patients showed significantly higher LVMI and peak aortic jet velocity, and smaller aortic valve area.
- ECG criteria exhibited low sensitivity (6%-36.9%) but high specificity (up to 100%), with Cornell Voltage criteria showing the best sensitivity and correlation with LVMI.
Conclusions:
- Electrocardiographic criteria for LVH have poor sensitivity in identifying TTE-confirmed LVH in moderate to severe AS.
- ECG findings correlate weakly with TTE indices of LVH and AS severity markers.
Background:
Aortic valve stenosis (AS) generates a chronic pressure overload that induces left ventricular hypertrophy (LVH). The aim of this study was to assess the prevalence of the electrocardiographic criteria for LVH in patients with clinically significant AS and to evaluate the relationship between the ECG criteria for LVH and echocardiographic parameters.
Methods:
The clinical data of 95 patients with moderate to severe AS were retrospectively analyzed. Eight ECG criteria for LVH were used and compared to the results of transthoracic echocardiography (TTE).
Results:
In 59% of patients, at least one of the ECG criteria for LVH was found. These patients had a greater LVMI (142.1 ± 35.6 vs. 124.1 ± 22.5 g/m2 , p = 0.01) and peak aortic jet velocity (4.2 ± 0.8 vs. 3.8 ± 0.9 m/s, p = 0.01) along with smaller aortic valve area (0.72 ± 0.28 vs. 0.86 ± 0.22 cm2 , p = 0.02) compared to patients with a negative ECG for LVH. The ECG parameters had a low sensitivity (6%-36.9%) with a specificity of up to 100%. The Cornell Voltage criteria had the best sensitivity with a specificity of 63.6% and the highest correlation with the LVMI (r = 0.38, p < 0.001). All of the ECG parameters correlated positively with the peak aortic jet velocity as well as with the mean aortic gradient.
Conclusion:
The electrocardiographic criteria for LVH in patients with moderate or severe AS have a poor sensitivity in identifying LVH confirmed by TTE. The values of the selected ECG criteria for LVH correlate weakly with both the TTE indices of LVH and the markers of AS severity.
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