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The Intersection of Physical Function, Cognitive Performance, Aging, and Multiple Sclerosis: A Cross-sectional

Rachel E Bollaert1, Brian M Sandroff2, Elizabeth A L Stine-Morrow3

  • 1Program in Exercise Science, Department of Physical Therapy, Marquette University, Milwaukee, Wisconsin.

Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology
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Summary
This summary is machine-generated.

Physical function and information processing speed are strongly linked in older adults with multiple sclerosis (MS). This highlights the importance of considering both in research and potential interventions for this population.

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Area of Science:

  • Neurology
  • Gerontology
  • Rehabilitation Science

Background:

  • Older adults with multiple sclerosis (MS) exhibit diminished physical and cognitive function compared to their healthy peers and younger individuals with MS.
  • The relationship between physical and cognitive function in older adults with MS remains under-explored.

Purpose of the Study:

  • To investigate the associations between physical function (walking speed, endurance, mobility) and cognitive function (information processing speed, verbal memory) in older adults with MS.
  • To compare these associations with those found in healthy older adults.

Main Methods:

  • Physical and cognitive function assessments were conducted on 40 older adults with MS and 40 healthy controls.
  • Pearson correlations and linear regression analyses were employed to examine bivariate and independent associations.

Main Results:

  • Significant correlations were observed between all physical function variables and information processing speed in the overall sample, primarily driven by the MS group.
  • Information processing speed and education level were significant predictors of physical function in older adults with MS, independent of demographic factors.

Conclusions:

  • A strong correlation exists between physical function and information processing speed in older adults with MS.
  • Future research should explore the neurobehavioral mechanisms and behavioral strategies for improving both physical and cognitive functions concurrently in this demographic.