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Updated: Jan 27, 2026
09:17
Using Retinal Imaging to Study Dementia
Published on: November 6, 2017
22.2K
Post-stroke dementia is associated with increased subsequent all-cause mortality: A population-based cohort study
Tomor Harnod1, Cheng-Li Lin2, Chung Y Hsu3
1Department of Neurosurgery, Hualien Tzu Chi General Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; College of Medicine, Tzu Chi University, Hualien, Taiwan.
Atherosclerosis
|March 22, 2019
Summary
Patients with post-stroke dementia (PSD) face a significantly higher mortality risk. This condition also leads to increased hospitalizations and healthcare utilization, highlighting the need for improved post-stroke care strategies.
Area of Science:
- Neurology
- Public Health
- Geriatrics
Background:
- Post-stroke dementia (PSD) is a common complication following stroke.
- Understanding the long-term mortality implications of PSD is crucial for patient management.
Purpose of the Study:
- To investigate the association between post-stroke dementia (PSD) and mortality risk in Taiwan.
- To analyze healthcare utilization patterns in patients with PSD.
Main Methods:
- A cohort study using Taiwan's National Health Insurance Research Database (2000-2012).
- Inclusion of patients aged ≥40 years diagnosed with stroke.
- Propensity score matching to compare PSD and post-stroke non-dementia (PSN) cohorts.
- Adjusted hazard ratios (aHRs) calculated for mortality risk.
Main Results:
- The incidence density rate of death was higher in the PSD cohort (148.7 per 1,000 person-years) compared to the PSN cohort (106.7 per 1,000 person-years).
- Patients with PSD had a significantly increased adjusted hazard ratio for death (aHR = 1.42; 95% CI = 1.34-1.50).
- PSD was associated with increased average hospital days and a higher frequency of medical visits.
Conclusions:
- Post-stroke dementia is associated with a substantially increased risk of mortality.
- Patients with PSD experience greater healthcare resource utilization.
- Findings underscore the importance of addressing dementia post-stroke to improve patient survival and healthcare planning.
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