Related Experiment Video
Updated: Jan 27, 2026

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
Published on: December 2, 2015
Keeping children safe: a model for predicting families at risk for recurrent childhood injuries
A Sever1, J Essa-Hadad1, A Luder2
1Department of Population Health, Azrieli Faculty of Medicine, Bar Ilan University, POB 1589, Henrietta Szold 8 Safed 1311502, Israel.
Insights
This study identified eight key risk factors for recurrent unintentional injuries (UI) in children, enabling better identification of families needing public health interventions to prevent repeat injuries.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Existing research on recurrent unintentional injury (UI) primarily focuses on individual child factors, neglecting family-level risks.
- Identifying families at high risk is crucial for developing targeted public health interventions.
Purpose of the Study:
- To develop a statistical model for identifying families at the highest risk of recurrent unintentional injuries in children.
- To inform the targeting of public health interventions for injury prevention.
Main Methods:
- A retrospective birth cohort study utilized hospital and emergency room (ER) records of children born between 2005 and 2012.
- Negative binomial regression analyzed predictive factors for recurrent child UI using a two-period approach.
- Sensitivity analyses were performed to ensure the model's robustness.
Main Results:
- Eight significant predictive factors for child injury were identified (P < 0.05): male gender, prior UI visits, illness visits, age 36-59 months, low birth weight (<1500 g), maternal ER visits, siblings' UI visits, and number of younger siblings.
- Some factors are established predictors, while others, like maternal ER visits and siblings' UI visits, are novel.
- Five factors remained significant across all sensitivity analyses, indicating model stability.
Conclusions:
- The identified factors can predict a child's risk of repeat UI and a family's cumulative UI risk.
- This novel statistical model offers a valuable approach for targeting public health interventions to high-risk families.
- Early identification and intervention can mitigate the burden of recurrent unintentional injuries.
Objective:
Existing research on recurrent unintentional injury (UI) focuses on the individual child rather than family risks. This study developed a statistical model for identifying families at highest risk, for potential use in targeting public health interventions.
Study Design:
A retrospective birth cohort study of hospital and emergency room (ER) medical records of children born in Ziv hospital between 2005 and 2012, attending ER for UI between 2005 and 2015, was conducted.
Methods:
Using national IDs, we assigned children to mothers and created the family entity. Data were divided into two time periods. Negative binomial regression was used to examine predictive factors in the first period for recurrent child UI in the second period. Sensitivity analyses were conducted to examine the model's robustness.
Results:
Eight predictive factors for child injury (P < 0.05) were found: male gender, the number of UI visits, the number of illness visits, age 36-59 months, birth weight <1500 g, maternal ER visits, siblings' UI visits, and the number of younger siblings. Some predictive factors are documented in the literature; others are novel. Five were significant in all sensitivity analyses.
Conclusions:
These factors can assist in predicting risk for a child's repeat UI and family's cumulative UI risk. The model may offer a valuable and novel approach to targeting interventions for families at highest risk.
Related Concept Videos
Protein Families
Protein Families
Gene Families
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Gene Families
Family Therapy
Strategic Family Therapy
Strategic family therapy emphasizes resolving communication barriers and improving problem-solving abilities...
Predicting Molecular Geometry

