Novel polysiloxane-based rhodamine B fluorescent probe for selectively detection of Al³⁺ and its application in living-cell and zebrafish imaging

Polysiloxanes have excellent stability and biological relevance and are suitable for biological research. However, there were few polysiloxane-based fluorescent probes for bioimaging. This report successfully designed a new polysiloxane-based polymer fluorescent probe (RB-1) for the first time as a "turn-on" fluorescent probe response to Al³⁺ ion with highly sensitive and selectivity. Importantly, this probe could also apply both in cell and zebrafish imaging, indicating the huge application development prospects of polysiloxane-based fluorescent probes in future.