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Related Experiment Video

Updated: Jan 27, 2026

Imaging Cleared Intact Biological Systems at a Cellular Level by 3DISCO

Imaging Cleared Intact Biological Systems at a Cellular Level by 3DISCO

Published on: July 7, 2014

Cellular Dynamics, a Systems Biology Bottleneck.

Gerrit T S Beemster¹

¹Laboratory for Integrated Molecular Plant Physiology Research (IMPRES), Department of Biology, University of Antwerp, Antwerp 2020, Belgium.

Trends in Plant Science

|March 26, 2019

Summary

Understanding plant growth requires studying cell division and expansion. New microscopy and modeling reveal key regulatory mechanisms in plant organs.

Area of Science:

Plant biology
Developmental biology
Cellular processes

Background:

Mechanistic understanding of plant growth regulation is incomplete.
Requires integrated study of cell division, cell expansion, and molecular mechanisms.

Purpose of the Study:

To provide new insights into plant growth regulatory mechanisms.
To quantify cell division and expansion in individual cells within growing organs.

Main Methods:

Time-lapse confocal microscopy.
Quantitative analysis of cellular processes.
Multiscale modeling.

Main Results:

Quantification of cell division and expansion in individual cells.

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Imaging Cleared Intact Biological Systems at a Cellular Level by 3DISCO

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Published on: July 7, 2014

The Use of Chemostats in Microbial Systems Biology

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BioMEMS and Cellular Biology: Perspectives and Applications

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Integration of cellular dynamics with organ growth.

Identification of novel regulatory insights.

Conclusions:

Combined microscopy and modeling offer profound insights into plant growth regulation.
Understanding cellular dynamics is crucial for deciphering organ-level growth.