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Updated: Jan 27, 2026
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Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes
Published on: February 8, 2018
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Advances in Whole-Eye Optical Coherence Tomography Imaging
Anthony N Kuo1, Ryan P McNabb, Joseph A Izatt
1From the Department of Ophthalmology, Duke University School of Medicine, Durham, and Department of Biomedical Engineering, Duke University, Durham, NC, United States.
Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
|March 26, 2019
Summary
New whole-eye optical coherence tomography (OCT) systems can now image the entire eye at once, unlike older systems that focused on either the anterior segment or retina separately. This advancement enables comprehensive eye imaging for various clinical applications.
Area of Science:
- Ophthalmology
- Biomedical Imaging
- Optical Engineering
Background:
- Current optical coherence tomography (OCT) systems are limited to imaging either the anterior segment or the retina due to specialized optical designs and depth limitations.
- This compartmentalized imaging approach prevents a holistic view of ocular structures.
Purpose of the Study:
- To introduce and describe the capabilities of novel "whole-eye" optical coherence tomography (OCT) systems.
- To highlight the advantages of integrated ocular imaging over segmented approaches.
Main Methods:
- Development of advanced OCT systems capable of imaging the entire ocular volume.
- Utilizing optical designs that overcome previous limitations in imaging depth and anterior/posterior segment specificity.
Main Results:
- Demonstration of OCT systems that can simultaneously capture detailed images of both the anterior and posterior segments of the eye.
- Validation of "whole-eye" OCT for applications including ocular biometry and myopia analysis.
Conclusions:
- Whole-eye OCT represents a significant advancement, enabling the eye to be viewed as a complete, integrated organ.
- This technology expands the potential for diagnosing and managing various ocular conditions by providing comprehensive anatomical data.
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