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Related Concept Videos

Polytene Chromosomes02:04

Polytene Chromosomes

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Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also...
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Chromosome Structure02:40

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A functional eukaryotic chromosome must contain three elements: a centromere, telomeres, and numerous origins of replication.
The centromere is a DNA sequence that links sister chromatids. This is also where kinetochores, protein complexes to which spindle microtubules attach, are constructed after the chromosome is replicated. The kinetochores allow the spindle microtubules to move the chromosomes within the cell during cell division.
Telomeres consist of non-coding repetitive nucleotide...
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Chromosome Structure02:40

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Lampbrush Chromosomes01:51

Lampbrush Chromosomes

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In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops...
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Lampbrush Chromosomes01:51

Lampbrush Chromosomes

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Chromosome Replication02:31

Chromosome Replication

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Before a cell can divide, it must accurately replicate all of its chromosomes, including the DNA and its associated histone and non-histone proteins.  This process begins at numerous origins of replication during the S phase of the cell cycle in each of a cell’s chromosomes simultaneously. Certain nucleotides can act as origins of replication, but these sequences are not well defined - especially in complex, multi-cellular, eukaryotic species. The length of DNA that spans an origin...
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Related Experiment Video

Updated: Jan 27, 2026

Micromanipulation of Chromosomes in Insect Spermatocytes
05:45

Micromanipulation of Chromosomes in Insect Spermatocytes

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Cromosoma 13 en anillo.

Francisco Cammarata-Scalisi1, Yajaira Briceño2, Edymar Cegarra3

  • 1Unidad de Genética Médica, Departamento de Puericultura y Pediatría, Facultad de Medicina, Universidad de Los Andes.

Boletin Medico Del Hospital Infantil De Mexico
|March 26, 2019
PubMed
Summary

Ring chromosome 13 (r(13)) is a rare genetic disorder causing developmental delays, microcephaly, and distinctive physical features. This case highlights the diagnostic challenges and importance of genetic counseling for r(13).

Area of Science:

  • Cytogenetics
  • Clinical Genetics
  • Developmental Pediatrics

Background:

  • Ring chromosome 13 is a rare cytogenetic abnormality.
  • It is associated with growth and psychomotor retardation, cognitive deficits, microcephaly, dysmorphism, genital anomalies, and thumb hypoplasia.
Keywords:
46, XY, r (13)Asesoramiento genéticoClinicClínicaCromosoma 13 en anilloGenetic counselingRing chromosome 13

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