Related Experiment Video
Updated: Jan 27, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
The Natural Growth Rate of Skull Base Meningiomas Compared With Non-Skull Base Meningiomas
Xiang Yao1, Ting Wei2, Haoran Zhang1
1Department of Radiology, The Xiang'An Hospital of Xia Men Uneversity, Xia Men.
Abstract:
In the present study, the authors assessed the differences in natural growth rates between skull base and non-skull base meningiomas by meta-analysis. Studies investigating meningioma growth rate were compiled from PubMed, Embase, Cochrane Central Register of Controlled Trials, Chinese Biomedical Literature database, and the China National Knowledge Infrastructure databases. A systematic review and meta-analysis of the collected literature were conducted using Stata 12.0 software. A total of 7 observational cohort studies, including 361 patients with untreated meningiomas, were included in the study. Meta-analysis showed that the weighted mean difference for absolute growth rate (years), relative growth rate (years), and doubling time (month) were 0.42 (95% confidence interval [CI]: 0.20-0.64, P <.0001), 1.08 (95%CI: 0.85-1.32, P <.0001), and -0.56 [95%CI: (-0.78)-(-0.33), P <.0001)] respectively. These findings indicate that the natural growth rate of skull base meningioma is less than that of non-skull base meningioma.
Related Concept Videos
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Overview of the Skull
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
Nature and Nurture
Base Excision Repair
The first step of...
Lewis Acids and Bases
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
Weak Base Solutions

