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Get Cultured: Eat Bacteria.

Todd Robert Klaenhammer1

  • 1Department of Food, Bioprocessing & Nutrition Sciences, North Carolina State University, Raleigh, North Carolina 27695, USA;

Annual Review of Food Science and Technology
|March 26, 2019
PubMed
Summary

Pioneering genomic applications in food microbiology, this research advanced the use of beneficial lactic acid bacteria for food preservation and probiotics. These advancements also paved the way for novel oral delivery systems for vaccines and biotherapeutics.

Keywords:
Klaenhammerautobiographybiotechnologyfood sciencegenomicslactic acid bacteriamicrobiologyprebioticsprobiotics

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Area of Science:

  • Food Microbiology
  • Genomics
  • Biotechnology

Background:

  • The Klaenhammer group at North Carolina State University has made significant contributions to food microbiology.
  • Pioneered genomic applications for beneficial lactic acid bacteria.
  • Dr. Todd Klaenhammer's leadership recognized by election to the National Academy of Sciences.

Purpose of the Study:

  • To highlight the pioneering work in genomic applications for food microbiology.
  • To showcase the translational applications of beneficial microbes in food and health.
  • To emphasize the development of novel delivery systems for biotherapeutics.

Main Methods:

  • Utilized basic microbiology and genomic approaches.
  • Focused on lactic acid bacteria as starter cultures and probiotics.
  • Explored applications in food preservation and oral delivery systems.

Main Results:

  • Established a foundation for using beneficial microbes in food.
  • Demonstrated potential for probiotics and food preservation.
  • Paved the way for oral delivery of vaccines and biotherapeutics.

Conclusions:

  • Genomic approaches have transformed the application of beneficial microbes in food.
  • The research has broad implications for food safety, health, and biopharmaceutical delivery.
  • The work has been recognized with numerous prestigious awards and honors.