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Updated: Jan 27, 2026

Robot-Assisted Kidney Transplantation
Published on: July 19, 2021
Pyomyositis in a Patient with IgA Nephropathy and Kidney Transplant
M Xipell1, P Ventura-Aguiar1, I Revuelta1
1Nephrology and Renal Transplantation Department, Hospital Clinic of Barcelona, Experimental Laboratory in Nephrology and Kidney Transplant (LENIT), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Spain.
Abstract:
Infections are among the most common complications transplant physicians face when dealing with solid organ transplant recipients. We present a case of pyomyositis caused by Staphylococcus aureus in a patient with IgA nephropathy and a kidney transplant, under treatment with mTOR inhibitors and prednisone. This entity is a rare intramuscular infection, given the resistance of healthy muscle to colonization. We review the most frequent agents, the diagnostic algorithm, and therapeutic alternatives. We also comment on the role of mTOR inhibitors in this case as possible predisposing factor for the infection.
Insights
A kidney transplant patient developed pyomyositis, a rare muscle infection, caused by Staphylococcus aureus. mTOR inhibitors may have contributed to this serious complication in transplant recipients.
Area of Science:
- Infectious Diseases
- Nephrology
- Transplantation
Background:
- Solid organ transplant recipients face frequent infections.
- Pyomyositis is a rare intramuscular infection, typically seen in immunocompromised individuals.
Observation:
- A case of pyomyositis caused by Staphylococcus aureus in a kidney transplant patient with IgA nephropathy is presented.
- The patient was on mTOR inhibitors and prednisone therapy.
Findings:
- Staphylococcus aureus was identified as the causative agent of pyomyositis.
- The review covers common infectious agents, diagnostic approaches, and treatments for pyomyositis.
- The potential role of mTOR inhibitors as a predisposing factor for infection is discussed.
Implications:
- Highlights the risk of rare infections like pyomyositis in transplant patients on immunosuppressants.
- Suggests considering mTOR inhibitors as a potential risk factor for pyomyositis.
- Emphasizes the need for vigilant monitoring and prompt diagnosis of infections in transplant recipients.
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Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure
Kidney Transplant III: Nursing Management
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