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Evaluation of eltrombopag in patients with aplastic anemia in real-world experience
Akiko Konishi1,2, Aya Nakaya1,2, Shinya Fujita1,2
1First Department of Internal Medicine, Kansai Medical University, Japan.
Background:
Although eltrombopag has recently been approved for treating AA, the effects of its clinical use remain unknown.
Methods:
We retrospectively analyzed 11 patients with AA, who had been treated with eltrombopag from August 2017 to May 2018.
Results:
Overall response rate was 55%. There was tri-lineage recovery in four patients and platelet recovery in two. The reactive time was within 8 weeks after treatment initiation. Stage at the initial assessment, the neutrophil-to-lymphocyte ratio and platelet counts were significantly different between the responders and non-responders.
Conclusion:
Eltrombopag is a promising agent for treating patients with any degree of AA.
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