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Antitumor Activity of Fermented Colostrum and Milk
K M Shahani1, B A Friend1, P J Bailey1
1Department of Food Science and Technology, University of Nebraska, Lincoln, Nebraska 68583-0919.
Abstract:
Male Swiss mice, implanted with Ehrlich ascites tumor cells, were fed each of the following test materials: fresh bovine colostrum, colostrum cultured with Lactobacillus acidophilus , colostrum cultured with Lactobacillus bulgaricus , colostrum cultured with L. bulgaricus and Streptococcus thermophilus , milk cultured with L. acidophilus and milk cultured with L. bulgaricus . Fresh colostrum had no significant effect when fed ad libitum for 7 consecutive days after tumor implantation. Colostrum fermented with L. acidophilus , L. bulgaricus or yogurt culture significantly (P< 0.05) inhibited tumor cell proliferation as indicated by a 16 to 40% decrease in cell counts and a 13 to 35% decrease in DNA synthesis. Similar effects were noted for whole milk fermented with either L. acidophilus or L. bulgaricus .
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