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Proximal humerus chondrosarcoma.Long-term clinical and oncological outcomes
J I Albergo1, G L Farfalli Luis1, M A Ayerza1
1Servicio de Ortopedia y Traumatología - Sector de Ortopedia Oncológica y trasplantes óseos, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Summary
Proximal humerus chondrosarcoma shows high survival rates with surgery. Curettage and bone grafting are safe for grade 1 tumors, while reconstruction after resection has significant failure rates.
Area of Science:
- Orthopedic Oncology
- Surgical Oncology
- Bone Sarcoma Research
Background:
- Proximal humerus is a common site for primary bone sarcomas.
- Chondrosarcoma accounts for 15% of these tumors.
- Limited reports exist on proximal humerus chondrosarcoma.
Purpose of the Study:
- Analyze surgical and oncological outcomes in proximal humerus chondrosarcoma.
- Evaluate long-term results of surgical treatment.
- Assess complication and recurrence rates.
Main Methods:
- Retrospective review of patients with proximal humerus chondrosarcoma treated surgically.
- Analysis of overall survival and local recurrence rates.
- Recording of post-operative complications and limb salvage surgery failures.
Main Results:
- 37 patients included; median age 46, 65% female.
- 10-year overall survival 94.5%, event-free survival 84.5%.
- Local recurrence rate 13% (only in higher grades); 5-year reconstruction failure rate 27%.
Conclusions:
- Proximal humerus chondrosarcoma demonstrates high survival rates.
- Curettage and bone grafting are safe for grade 1 tumors, with low complication and recurrence risk.
- Reconstruction after wide resection has substantial failure rates (27% at 5 years, 34% at 10 years).
Keywords:
ChondrosarcomaCirugía de salvamento de la extremidadCondrosarcomaCurettageHúmero proximalLimb salvage surgeryProximal humerusRaspadoMore Related Videos
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