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Updated: Jan 27, 2026

Synthesis and Evaluation of a Ruthenium-based Mitochondrial Calcium Uptake Inhibitor
Published on: October 26, 2017
A photochemical route to a square planar, ruthenium(iv)-bis(imide)
Kelly E Aldrich1, Aaron L Odom
1Department of Chemistry, Michigan State University, 578 S Shaw Ln, East Lansing, MI 48824, USA. odom@chemistry.msu.edu.
Abstract:
The square planar, ruthenium(iv) bis(imide) trans-Ru(NAr)2(PMe3)2 can be prepared photochemically from a Ru(ii) tetrazene. Additionally, we report reactivity of the Ru(iv) bis(imide) species, similar to that of the osmium derivative. Attempts to change both imide group and phosphine substituents are presented, which led to alternative reactivity.
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