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High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage

Ian M Slaymaker1, Pablo Mesa2, Max J Kellner3

  • 1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Cell Reports
|March 28, 2019
PubMed

Keywords:
CRISPR-Cas9 systemCas13bRNA-targetingcrystal structuretype VI CRISPR

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