Related Experiment Video
Updated: Jan 27, 2026
06:36
Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue
Published on: May 1, 2019
7.4K
[Problems for the conversion therapy in advanced gastric cancer].
1Department of Surgical Oncology, the First Affiliated Hospital of China Medical University, Shenyang 110001, China.
Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]
|March 28, 2019
Summary
Conversion therapy shows promise for advanced gastric cancer patients, improving survival. Future precision medicine approaches aim to refine patient selection and surgical roles for better outcomes in this challenging cancer.
Area of Science:
- Oncology
- Surgical Oncology
- Gastroenterology
Background:
- Advanced gastric cancer presents a significant clinical challenge with poor patient prognosis.
- Traditional treatments like adjuvant chemotherapy and palliative surgery offer limited efficacy.
- Emerging conversion therapy strategies are improving survival rates in recent years.
Purpose of the Study:
- To review the current challenges and future directions of conversion therapy for advanced gastric cancer.
- To discuss the definition, patient selection, and surgical role in conversion therapy.
- To explore the potential of precision medicine in optimizing conversion therapy outcomes.
Main Methods:
- Literature review of recent advancements in gastric cancer treatment.
- Analysis of current definitions and challenges in conversion therapy.
- Discussion of precision medicine applications in advanced gastric cancer.
Main Results:
- Conversion therapy has demonstrated improved survival for advanced gastric cancer.
- Key challenges include defining advanced gastric cancer and conversion therapy criteria.
- Optimizing patient selection and the role of surgery are critical for success.
Conclusions:
- Conversion therapy represents a promising approach for advanced gastric cancer.
- Further research is needed to standardize definitions and patient selection criteria.
- Precision medicine holds significant potential to enhance conversion therapy efficacy and patient benefit.
More Related Videos
Related Concept Videos
02:49Cancer Therapies
9.9K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
9.9K
02:57Targeted Cancer Therapies
8.7K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
8.7K
02:08Gene Conversion
10.6K
Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
10.6K
02:08Gene Conversion
3.0K
3.0K
01:16Gastric Motility
3.0K
Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
3.0K
01:36Conversion of Units
35.7K
Sometimes, there is a need to convert from one unit to another one. For instance, reading a cookbook in which quantities are expressed in units of liters or ounces may require conversion of quantities to cups. Or, when looking up directions on how to get to a location, we may be interested to know how many miles we are going to walk. In this case, we would have to convert units of feet or meters to miles.
The first step in the unit conversion is to list the given units and the units required...
The first step in the unit conversion is to list the given units and the units required...
35.7K